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June 2023 Neurology Recall: Biomarker Discovery in Parkinson Disease

Neurology® Podcast

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The Main Primary Take-Home Lesson From This Project

Jeffrey Toobin: Andrew welcome to the podcast. You and your colleagues looked at cerebrospinal fluid of patients in the PPMI cohort specifically looking at results on these alpha-synuclein seed amplification assays. In that group you were looking at both patients with diagnosed Parkinson's disease but also prodromal or quote-unquote pre-motor Parkinson's. So there's a lot going on with these various cohorts and comparisons. What would you tell colleagues is the main primary take-home lesson from this project and from this paper?Andrew Wexler: If you allow me I would say that our three take-home lessons from the paper that I'd like to

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