FOXP3 and IPEX syndrome

The Immune team discusses the groundbreaking discoveries of regulatory T cells, which was the topic of the 2025 Nobel Prize in Physiology or Medicine.

Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker

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• MicrobeTV Discord Server
• Sakaguchi lab paper on FoxP3 and regulatory T cells (Science 2003)
• Brunkow and Ramsdell description of scurfy mouse mutation (Nature 2001)
• Nobel Prize writeup on Treg discoveries
• Time stamps by Jolene Ramsey. Thanks!

Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv

Information on this podcast should not be construed as medical advice.