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Cancer Biology: Metabolism, Mitochondria & Energy | Thomas Seyfried | 224

Mind & Matter

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Rethinking Cancer Origins: Metabolism vs. Mutation

This chapter explores the competing theories on cancer origins, contrasting the somatic mutation theory with the mitochondrial metabolic theory rooted in Warburg's energy production concepts. It highlights recent research that challenges assumptions about ATP production and oxygen consumption in cancer cells, revealing their unique metabolic adaptations. By examining the nuances of energy pathways and the role of metabolites, the chapter advocates for a reevaluation of existing cancer biology paradigms.

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