The Role of Insulin in Exercise

There's a lot of there are direct roles at the liver. And then there are also indirect signals that's that set the tone for how the liver is going to respond. So, I think they're all potentially important but as you say, it's a big integrated response. It's hard to identify anyone mechanism as the single controller.

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Dr Glenn McConell chats with Professor David Wasserman from Vanderbilt University in Nashville, Tennessee, USA. David is recognised as an absolute authority on glucose homeostasis. His research focuses on how the system acts to protect sugar levels during exercise and disease. This talk is wide ranging with a focus on the liver. We discuss the large range of roles of the liver, how it maintains blood glucose levels at rest and in particular during exercise. The role of circulating hormones in the regulation of liver glucose output during exercise is a focus. Professor Wasserman has been at the forefront of this aspect of hormonal research for over 30 years. We then discuss insulin resistance and the liver and how exercise can increase insulin sensitivity (reduce insulin resistance) in various organs, including the liver. In addition, we touch on organ cross talk during exercise. David's father, Karlman Wasserman was a legend in exercise physiology and well known for his anaerobic threshold concept. David proudly discusses how he was also a very well regarded and internationally renowned pulmonary physician who saved many lives, including once saving a woman's life who was choking in a restaurant, using his swiss army knife and a straw!

Inside Exercise brings to you the who's who of exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.

The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.

He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).

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