Diagnosis and Management of Multiple Myeloma
JAMA Clinical Reviews
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The Complications of Multiple Mialoma and Renal Disfunction
The complications of the disease itself, in particular, are the four classic ones that we abbreviate as crab. The c for high calcium, r for renal disfunction, a for anemia, and b for bony destruction. Many patients present with back pain and severe compression fractures. Another complication is what' called plasmasitomus. Rarely the disease can go to the brain. That's quite uncommon. Now, there are also complications of therapy. Even though these drugs are well tolerated, there are some complications.
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