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Steroids in Septic Shock: The Approach Trial
An in-depth analysis of the Approach trial involving hydrocortisone and fluutrocortisone in septic shock, highlighting the improvements in 90-day survival compared to placebo. The chapter explores ongoing debates regarding the timing and severity of steroids in septic shock treatment, emphasizing the importance of evaluating secondary analyses and stratifying subgroups for proper randomization.
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