
Steve Hsu Q&A: Complex trait prediction in Genomics, and Genomic Prediction / Embryo Selection
Manifold
Is There Still a Drop Off in Prediction Power in Europeans?
There still is a significant drop off in prediction power when you try to use a predictor trained in europeans on a more distant ancestry. Now i focus on height because that's a very it's kind of a convenient venotype for a number of reasons. So two twins who have the same dione but are raised in different families, they'll tend to be within something like half an inch or an inch of each other in height. And so it's obviously a superheritable trait. That was the first thing we characterized that we focused on in order to get the first big result.
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