Bone Marrow and Bony Pain

The idea that ostio clasts make the a bone more acitic to be able to absorb it. And that that contributes to pain. Dunosomab also, is something that like, affects this axis. It's not yet clear if you could inhibit that and actually cause a clinical benefit. You alluded to the antinflammatories and seroids a couple of times. I feel like whene i've treated patients who have bony metestatic pain.