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What causes cardiovascular disease (Lipid Series - Part 1) | Dr Thomas Dayspring

The Proof with Simon Hill

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Transytosis

The term transytosis comes up a lot in the literature, which essentially just means the movement of these APOB containing lipoproteins from the plasma like in the lumen of the artery through the endothelial cells or between them into the intima. The million dollar question is why do some get ingested by macrophages and others do not? That can occur with perfectly healthy endothelium for that particle to pass right through it. Most of the disease early on is in the wall of the artery,. It's not obstructing the arterial wall movement at all. Even people who have subtle elevations of C-reactive protein (CRP) are more likely to develop diabetes

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