2.5 Substance Use Disorders
Psychiatry Boot Camp
Understanding the Role of the Prefrontal Cortex in Substance Use Disorders
This chapter explores the role of the prefrontal cortex in substance use disorders and how it is driven by the limbic system, leading to cravings and preoccupation. It discusses the impact of adverse childhood experiences on the neurobiology of individuals with substance use disorders and highlights the influence of genetic and epigenetic risk factors on the development of executive functioning. The chapter also examines the effects of increased dopamine levels in substance use disorders, particularly in adolescence, and emphasizes the importance of safe consumption sites in supporting recovery.
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