The Six Pillars of Mitochondrial Health [#3 Episode of 2025!]
The Energy Code
Pillar 2: Mitochondrial Biogenesis
Mike explains biogenesis, PGC-1α, NRF1/2, TFAM and hormetic triggers like exercise, fasting and red light therapy.
This is the #3 episode from 2025. Enjoy!
-In this deep-dive episode of The Red Light Report, Dr. Mike Belkowski takes you beyond the basics to explore why mitochondrial function is the true driver of health—and disease. After contrasting centralized vs. decentralized health paradigms, he reveals the root causes and systemic effects of mitochondrial dysfunction, using vivid analogies like “rocks in a river” to explain electron leakage and oxidative stress. From there, Mike unpacks the Six Pillars of Mitochondrial Health:
1. Energy Production – ATP synthesis & structured “EZ” water batteries
2. Biogenesis – Growing new mitochondria via PGC-1α, NRF1/2, TFAM
3. Mitophagy – Recycling damaged mitochondria through PINK1/Parkin
4. Fusion/Fission – Dynamic balancing of mitochondrial networks
5. Oxidative Stress Protection – Internal and supplemental antioxidants
6. Light Interaction – How red/NIR light supercharges bioenergetics
Along the way, learn why methylene blue and red light therapy are synergistic brain- and mitochondria-boosters, why proper breathing and oxygen availability are non-negotiable, and how lifestyle tactics—from grounding to sun exposure—tie back to cellular power. Mike closes with a sneak peek at an upcoming all-in-one mitochondrial optimization product designed to tackle all six pillars at once.
If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)
As always, light up your health!
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00:00 – Introduction: Mitochondrial Health & Podcast Focus
02:14 – Centralized vs. Decentralized Health Paradigms
03:43 – Mitochondrial Dysfunction: Causes and Effects
05:11 – Six Pillars of Mitochondrial Function Overview
07:39 – Pillar 1: Energy Production (ATP & EZ Water)
09:02 – Methylene Blue: Brain Boost + Mitochondrial Synergy
19:15 – Root Causes of Disease via Mitochondrial Dysfunction
20:11 – Electron Transport Chain Analogy (Rocks in a River)
26:47 – Importance of Breathing & Oxygen for Mitochondria
28:19 – Pillar 2: Mitochondrial Biogenesis
33:25 – Pillar 3: Mitophagy (Mitochondrial Cleanup)
39:24 – Pillar 4: Mitochondrial Fusion & Fission
43:08 – Pillar 5: Free Radical & Oxidative Stress Protection
48:11 – Antioxidants: Internal & External Defenses
52:18 – Pillar 6: Light’s Impact on Mitochondria
58:29 – Light = Battery for Cells: Red/NIR Light & EZ Water
59:20 – Recap: The Six Pillars of Mitochondrial Health
01:00:17 – Tease for New Product: Optimizing All Six Pillars
01:02:13 – Final Thoughts: Pursuing the Mitochondrial Fountain of Youth
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Dr. Mike's #1 recommendations:
- Water products: Water & Wellness
- Grounding products: Earthing.com
- EMF-mitigating products: Somavedic
- Blue light-blocking glasses: Ra Optics
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