Episode 075: Intro to CAR-T, Bispecifics (BiTE), and Autologous Transplant
The Fellow on Call: The Heme/Onc Podcast
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Exploring CAR-T Therapy: Side Effects and Management Strategies
This chapter explores CAR-T therapy's mechanisms, focusing on the distinctions between CD28 and 4.1BB co-stimulatory domains. It highlights significant side effects such as cytokine release syndrome and neurotoxicity, stressing the need for patient monitoring and outlining initial treatment strategies.
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Transcript
