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Ep. 49: “Viruses and Aging” Featuring Dr. Clovis Palmer

The Immunology Podcast

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Car TZL Therapy

LAT and SLP 76 can be made into two different cars. And only upon co-expression does this car signal and they initiate TZL activation. This seems to really be the first model of true kind of and gating that they are because they're having other other types of car constructs or other synthetic constructs. But I think this is really, really cool because it really allows for much more specificity on this recognition of two different antigens on a tumor.

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