Jim talks with epidemiology expert Samuel Scarpino about the recent spread of H5N1 (bird flu) in dairy cows and its implications for public health. They discuss the historical context of H5N1, fatality rates, modeling the spread, network effects in disease transmission, current surveillance efforts, H5N1 transmission mechanisms, challenges of human respiratory transmission, lessons learned & mislearned from Covid-19, the current state of the H5N1 vaccine preparation, extreme pandemic response scenarios, Sam's current risk assessment, economic impacts including egg & dairy prices, recommendations for immediate action, and much more. Episode Transcript JRS Currents 099 - Sam Scarpino on Preparing for the Next Pandemic JRS Currents 047 - Samuel Scarpino on the Epidemiology of Covid-19 Center for Advanced Preparedness and Threat Response Simulation (CAPTRS) Global.health Metaculus Samuel Scarpino is the Director of AI + Life Sciences at the Institute for Experiential AI at Northeastern University and a Professor of the Practice in Health and Computer Sciences. He holds appointments in the Institute for Experiential AI and the Network Science, Global Resilience, and Roux Institutes. Prior to joining Northeastern in November 2022, Scarpino was the Vice President of Pathogen Surveillance at The Rockefeller Foundation and Chief Strategy Officer at Dharma Platform (a social impact, technology startup). Outside of these roles, he has over 10 years of experience translating research into decision support and data science/AI tools across diverse sectors from public health and clinical medicine to real estate and energy.