In this episode, Dr Adrian Lopresti speaks with cognitive neuroscientist and postdoctoral fellow Dr Diana Karamacoska to explore the evolving landscape of brain health and dementia prevention. With a personal connection to vascular dementia, Diana shares insights from Australia’s largest clinical trial investigating a novel herbal formulation combining panax ginseng, ginkgo, and saffron.
The discussion covers the biological distinctions between vascular dementia and Alzheimer’s, the role of lifestyle factors, and the emerging use of digital assessments and blood biomarkers. Diana explains the cognitive and systemic benefits of physical activity, diet, social connection, and mind-body practices like yoga and tai chi. The conversation also highlights nutrients and herbs showing promise for memory and neuroprotection, including B vitamins, ginkgo, curcumin, lutein, and zeaxanthin.
This episode offers practical, evidence-informed strategies for addressing cognitive ageing, vascular decline, and dementia risk—providing value not only for practitioners in clinical care, but also as a resource they can confidently share with patients.
Covered in this episode:
(00:53) Welcome Dr Diana Karamacoska
(02:00) Vascular dementia clinical trial
(06:14) Main drivers of dementia
(07:18) Symptoms of vascular dementia
(09:51) Environmental factors
(15:25) Cognitive assessment and performance
(23:01) What is normal process of ageing
(26:11) Physical activity and ageing
(28:46) Nutrition for brain health
(31:40) Herbal and nutritional supplementation
(36:15) Final remarks
Find today's transcript and show notes here:
https://www.bioceuticals.com.au/education/podcasts/intercepting-cognitive-decline-through-lifestyle-medicine
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