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TWiV 1213: Secrets of HepB cccDNA

This Week in Virology

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Chromatin Dynamics and CBL-137 Therapy

This chapter explores the interplay between chromatin assembly and transcription, focusing on the inhibitory effects of the drug CBL-137 on HPV and HBV transcription. It highlights the potential of CBL-137 as a therapeutic agent in treating chronic HBV infections by targeting chromatinization and discussing the complexities of current animal models in viral research.

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