Neurobiology and Management of Major Depressive Disorder

This chapter delves into the neurobiology of major depressive disorder, exploring the importance of plasticity, network connectivity, and cellular alterations. It discusses the common pathways and mechanisms of action for various treatments, highlighting the misconception of a serotonin deficiency and emphasizing the multifaceted nature of depression. The chapter also covers the management of depression, addressing psychotherapy and medication options, including SSRIs and alternative classes of medications.