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Cell Therapies of the Future with Dan Goodman

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CHAPTER

The Difference Between CRISPR-Cas9 and the Livery Mechanism

The current, mostly state of the art right now for cars is you put these cars on a viral vector. And that virus randomly integrates into your genome and each cell may even get more than one copy of your car. The difference here in this model that we used is that we used the ubiquitous and exciting CRISPR-Cas9 and the livery mechanism. We're putting the car at a specific place on the genome.

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