Investigating HLH cover image

Introduction to HLH

Investigating HLH

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Classification of HLH and Importance of Identifying Hyperinflammation

The chapter delves into the distinctions between primary and secondary HLH, emphasizing the significance of recognizing hyperinflammation and understanding the immune system's role in guiding treatment decisions. It also explores how individuals with what was historically labeled secondary HLH may have dysfunctional cell-killing pathways, discusses the confusion around HLH terminology, and explains the connection to macrophage activation syndrome.

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