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Episode 17. Acquired Aplastic Anemia

Blood Cancer Talks

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The Importance of Immunosuppressive Therapy in the Treatment of Plastic Pneumonia

Dason: Since the pathophysiology of T-cell mediated attack as an autoimmune disease for a plastic pneumonia was known, we've been studying immunosuppressive paradigms to knock back that T-cell attack. We started with ATG alone, not so hot. Then we added ATG in combination with cyclosporin and that was when we first saw a big jump in partial and even some complete response rates. Dason: In the United States, where we are in a privileged position quite often with availability of medicines, we choose horse as the frontline setting. For reasons that all be candid, I don't think anybody understands. People believe that in the upfront setting for

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