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Jul 7 2023 This Week in Cardiology

This Week in Cardiology

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The Benefits of Lipid Lowering in Primary Prevention

These results led to many news articles with headlines such as quote striking benefit of lipid lowering in primary prevention. Now fortunately and quite unusually was a strong rebuttal in an editorial accompanying the subgroup manuscript by Dr. Drew Kazi from the Beth Israel group in Boston. He noted that primary versus secondary prevention is one of 38 sub groups so by chance alone you will see positive subgroups. Recall that overall death was reduced in the primary prevention arm but when you look at the survival curves Ben Pinoic acid seems to reduce death right away. Of course this has to be spurious because if cholesterol lowering conferred a survival advantage it would take years to have an effect not days.

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