T cell expansion, PD‑L1 induction, and checkpoint dependence

TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space.

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• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint immunotherapy (Nature)
• People with some cancers live longer after mRNA vaccines (Nature)
• Immune checkpoint inhibitors (NCI)
• Broad immunity from influenza H5 vaccine (Nature)
• Derek Smith on antigenic cartography (TWiV 99 at 2:53)
• Letters read on TWiV 1265
• Timestamps by Jolene Ramsey. Thanks!

Kathy – Permethrin-treated baby wraps for malaria prevention and Phil Sharp and the Biotech Revolution Rich – Lydia Fairchild; Tetragametic Chimerism (NEJM) Alan – Warning Signs Vincent – radio.garden thanks to Kim!

Jamie – SkyCards by Flightradar24

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.