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David Baker | De Novo Protein Design

Foresight Institute Radio

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Using a Deep Learning Approach for Protein Design

The deep learning system is able to predict a probability distribution overall possible structures. It can also constrain parts of the protein to have shapes that are relevant for protein function. And we've we've solved structures now of three of them and actually the the C hallucinated sequences fold the hallucinated structures, which is pretty neat. But there's this tension between the deep learning models in my group and development and then Rosetta.

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