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Stiff-person syndrome

Practical Neurology Podcast

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The Diagnostic Dilemmas of Stiff Person Syndrome

This chapter explores the demographic patterns and diagnostic challenges of stiff person syndrome, particularly its prevalence in females aged 20 to 50. It emphasizes the confusion arising from neuropsychiatric symptoms that often lead to misdiagnosis, highlighting the role of specific antibody tests in confirming the syndrome. The discussion also touches on historical shifts in diagnosis and the complexities involved in linking stiff person syndrome with associated conditions and autoimmune factors.

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