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Inventing Base Editing with Doctors Nicole Gaudelli and Alexis Komor
FYI - For Your Innovation
Is Cas9 Really a CRISPR RNA Targeting Protein?
Nicole: I was definitely technology before the CRISPR based things that used app jimmers and recruited a AR to site. That's Maria Montiel's work. But there were definitely examples of targeted RNA editing just not using like CRISPR RNA targeting proteins. And like, those didn't really get acknowledged until the repair stuff came out because it was using a CRISPR protein. Nicole: Do you remember when one would like Maria stuff come out with like the box bead? Don't quote me, but I think it's 16, 2017.
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