Back after a summer break, Jame and Callum discuss the fascinating machine that is the MALDI-TOF. Matrix Assisted Laser Desorption Ionisation Time Of Flight mass spectrometry. We discuss the basics of how it functions, its application in the lab and some pros and cons of its use along with what the future may hold. Here are some relevant videos and papers:
- Exciting video of MALDI-TOF
https://www.youtube.com/watch?v=0jeFpXHZ8W0&ab_channel=BrukerDaltonics
- MALDI-TOF to detect MRSA https://www.frontiersin.org/articles/10.3389/fmicb.2020.00232/full
- Direct MALDI-TOF on blood cultures
https://www.spandidos-publications.com/10.3892/etm.2020.9365
- MALDI-TOF to detect CPE
https://www.frontiersin.org/articles/10.3389/fmicb.2021.789731/full
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