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Self Experiments In the Biochemically Unoptimized State

Mastering Nutrition

CHAPTER

The Effect of Biotin Deficiency on Glucose Tolerance

My biotin status was low in declining throughout this period. As it declined, my aspartate fell from flagglot to undetectable. My urinary ketones also shocked through the roof until the glucose tolerance has brought them down. These are all consistent with mild pyruvate carboxidase deficiency secondary at least in part to poor biotin status. Normally, this effect requires at least 1 gram of protein for B2 grams of carbohydrate. In a state of biotin deficiency, I now propose that at least 1gram of protein for every 1 gram of carbohydrate is needed to manifest this phenomenon. Moving forward, within 1 to 2 weeks, I will be able to write up

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