What Are the Benefits of NSAIDs?

Prostaglandins drop the threshold of a pain receptor. Usually it rests at negative 90 and needs to get to negative 55. But with the release of prostaglandins you can make it rest at like negative 70, negative 60. So it doesn't take much of a stimulus to trigger the pain signal. And important to say that prostaglandin they don't just play a role in pain, but also have a multitude of vascular effects which basically go hand in hand with inflammation.