
Ep. 182 "The Ins and Outs of JAK Inhibitors for Psoriatic Disease"
Psoriasis Uncovered
00:00
The Role of the Jack STAT Signaling Access in Psoriatic Disease
Jack STAT signaling access plays an important role in the intracellular cross-talks that signal the cascade of psoriatic disease and inflammation. Jack inhibitors may be less specific than biologics, such as anti-TNF agents or anti-interlucin-17 Agents. Ucba this ignib is a very selective Jack inhibitor, and it predominantly inhibits Jack 1. Tophositinib is a pan-Jack inhibitor, meaning that it inhibits Jack 1, Jack 2, and Jack 3.
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