ApoE Genetics and Lifetime Risk

Alzheimer’s disease is something many of us have seen affect our parents or grandparents, and it can feel like one of the most daunting challenges of ageing. But what if the narrative we’ve been told isn’t the whole truth? What if prevention – and even reversal – is possible?

Today, I’m delighted to welcome Dr Dale Bredesen to my Feel Better, Live More podcast, a conversation I’ve been looking forward to for many years. An internationally recognised expert in the mechanisms of neurodegenerative diseases, Dale’s career has been guided by a simple idea: that Alzheimer’s as we know it is not just preventable, but reversible. His dedicated pursuit of the science that makes this a reality has placed him at the vanguard of neurological research and led to the discoveries that today underlie the ReCODE Protocol™.

As well as multiple scientific publications, Dale has written about his findings and research in his first book: ‘The End of Alzheimer’s’, and his very latest book The Ageless Brain is a fantastic read about the simple things we can all do to improve the health of our brains today and across the duration of our lives.

In this powerful conversation, we discuss:   

• Why Alzheimer’s is not one single disease, but the end result of multiple systems in the body becoming imbalanced.
• The four stages of cognitive decline, and why identifying problems early can be a game-changer for prevention and treatment.
• The role of genetics, including ApoE4, in dementia risk, and why knowing your genetic status can empower you to take action.
• How inflammation, toxins and energy deficits all contribute to brain decline – and what we can do to address them.   
• Real-life case studies of people who have improved, even those in the early stages of dementia.
• The seven key lifestyle factors that can protect and optimise brain health at any age, from diet and exercise to sleep, stress and detoxification.

Dale also shares his vision of a future where cognitive decline is no longer seen as an inevitable part of ageing, but as something we can act on early – much like we already do with heart disease or cancer - and this opens the door to simple, everyday steps we can all take to protect our brains.

If you’ve witnessed Alzheimer’s in your family, it’s easy to feel powerless. But as Dale explains, there is much we can do to reduce our risk, support brain health and hold onto the connections and memories that matter most.

I hope you enjoy listening.

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Show notes https://drchatterjee.com/592

DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.