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Healthspan, Lifespan, and the Biology of Aging
a16z Podcast
Is It Possible to Improve Apulin Signaling in Mice and Invertebrates?
I still believe that the right preclinical experiments can be tremendously de-risking and value-creating as you move towards the clinic. Because yeah, there are experiments that you would do with mice that we wouldn't do with people. And there'll be probably many areas of mouse biology that overlaps with human biology. But at least for those things that are conserved, I think this is a great approach. We want to execute first-in-those targets with the most evidence that tick all the boxes.
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