Can medications like Ozempic and Mounjaro actually do more than help you lose weight? This minisode features highlights from our full conversation, which premiered October 7th, 2025. Watch the full episode here → https://youtu.be/AcVIiy201H4?si=nlaFL3JnoZHxQVFh

Dr. Rocio Salas-Whalen and I explore the difference between GLP-1, GIP, and triple-agonist drugs — and what’s next in obesity medicine, how estrogen changes after 40 drive midsection weight gain and inflammation, why GLP-1s reduce cancer and Alzheimer’s risk through anti-inflammatory and neuroprotective effects and how obesity and insulin resistance impact fertility and PCOS — and how GLP-1s can help.If you’ve ever wondered whether GLP-1s are just “weight loss shots” or a real step forward in metabolic and brain health — this “minisode” is a must-listen.

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Follow Dr. Salas-Whalen:

Instagram: @drsalaswhalen
TikTok: @drsalaswhalen
@strengthmd
@thedryrevolution

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I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics.

My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.

If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place.

Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0

Instagram: https://www.instagram.com/louisanicola_/

Twitter : https://twitter.com/louisanicola_

Topics discussed:

00:00 – Intro

00:04 – The Probiotic GLP-1 Myth

00:19 – The “iPhone Evolution” of GLP-1 Drugs

00:52 – GLP-1 vs GIP vs Triple Agonists Explained

01:24 – Phase 3 Results & Massive Weight Loss Outcomes

01:38 – The Role of Glucagon in Weight Loss

01:56 – Menopause, Estrogen & Midlife Weight Gain0

3:06 – The “Fat Shift” After 40

04:01 – Can You Combine HRT and GLP-1s?

06:17 – “Willpower” vs Biology in Obesity

07:49 – The Genetic and Hereditary Roots of Obesity

08:57 – Breaking the Transgenerational Cycle

09:30 – Thyroid Cancer Myths and GLP-1 Safety

10:49 – GLP-1s and Breast Cancer Prevention

12:06 – Inflammation as the Root of Disease

12:28 – Neuroprotection and Alzheimer’s Prevention

13:17 – GLP-1s, PCOS & Fertility Benefits

13:53 – The Positive Ripple Effect on Mental Health

14:21 – GLP-1s Reduce Alzheimer’s Risk by 33%

14:58 – The Future of Metabolic Health

Learn more about your ad choices. Visit megaphone.fm/adchoices

Ep. 139 – deaf jam

The Adam Friedland Show

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