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TWiV 853: COVID-19 clinical update #97 with Dr. Daniel Griffin

This Week in Virology

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Pax Lovid

Paxlovit is co packaged with ratonover as a potent c y p three a four inhibitor. Ratonovire will impact the metabolism of any drugs other than the ner matrever it is packaged with. Does this lengthy list of drug interactions prevent the use of pax lovid in the high risk populations who need it most? I'm curious about how many people who qualify having high risk for progressing to sevirkovi take one of these drugs. And if they can be safely treated with paxlovit, would many of these patients be limited to only receiving monoclones or the less effective monupirver,. Is this tha concern you are facing in the

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