Pcsk9 Inhibitor - What's Next?

The new kid on the block in this category i mentioned a little bit earlier is in chlisarum so it is a small interfering RNA that's targeted against pcsk9. The evolocomab and allaracomab are monoclonal antibodies targeting pcsK9 and this is preventing the synthesis of pcsk7. This also has that goll neck conjugation that really allows liver specific binding for patients with AS CBD or patients who have FH that haven't been able to get to LDL goal.