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Pandemic Inhumans
If omicron can spread that fast from a single point of release, any one malicious enough to deliberately cause a new pandemic would almost certainly release them in multiple travel hubs. Once one person sets the example, than many more people who are mentally ill or captive to horrific ideology would be more likely to do it now that they know that it's possible. In general, i'm not super worried about civilization falling apart because of a single natural pendemic virus. But if you're talking releasing aid at once, that might be another story, depending on how bad they are.