Amazon x OpenAI, Ford's EV Reality Check, Kushner Drops WB Bid | Sarah Guo, David Senra, Doug O'Laughlin, Doug Bernauer, Jacob Effron, Logan Kilpatrick
TBPN
Jacob Effron on AI applications and infrastructure
Jacob surveys AI application progress, infrastructure focus for 2026, and opportunities across robotics and healthcare.
- (02:12) - Ford's EV Reality Check
- (21:03) - Amazon x OpenAI
- (33:13) - Kushner Drops WB Bid
- (39:53) - š¯•¸ Timeline Reactions
- (57:33) - Sarah Guo is the founder and managing partner of Conviction, an early-stage venture firm focused on backing transformative software and AI companies. Sheā€™s known for combining deep technical fluency with a strong product lens, shaped by her experience as a partner at Greylock and as a former Facebook product leader.
- (01:32:29) - Doug O'Laughlin an expert in artificial intelligence and data center infrastructure, discusses Amazon's strategic partnership with OpenAI, emphasizing Amazon's superior execution in data center expansion and power availability. He highlights the challenges of integrating multiple computing platforms, noting that while diversification can reduce costs, it requires significant effort. Doug also expresses skepticism about the feasibility of space-based data centers, citing current difficulties in terrestrial model training and infrastructure development.
- (01:55:04) - Doug Bernauer, CEO and founder of Radiant, a company developing portable nuclear microreactors, discussed the company's progress in building their first reactor, which is set to become the first new design to go critical at Idaho National Laboratory since 1977. He highlighted securing a contract with Equinix for 20 units and a deal with the U.S. Air Force through the Defense Innovation Unit, emphasizing the role of nuclear energy in driving prosperity by providing power wherever needed. Bernauer also announced over $300 million in new funding, led by Draper Associates and Boost VC, to accelerate commercialization efforts, including constructing a mass-production facility in Tennessee.
- (02:09:01) - Jacob Effron, Managing Director at Redpoint Ventures, focuses on AI, enterprise software, and healthcare investments. In the conversation, he discusses the current state and future prospects of AI applications, the evolving venture capital landscape, and the potential impact of AI on various industries, including robotics and consumer hardware. He also shares insights on the challenges and opportunities in AI infrastructure development and the role of large tech companies in the AI ecosystem.
- (02:31:18) - Logan Kilpatrick, the product lead for Google AI Studio, discusses the launch of Gemini 3 Flash, highlighting its enhanced speed and efficiency compared to previous models. He emphasizes that Gemini 3 Flash offers advanced multimodal reasoning capabilities, enabling users to process and understand various forms of information more effectively. Kilpatrick also notes that this model is more cost-effective, making it accessible to a broader range of users and applications.
- (02:44:17) - David Senra is the creator and host of the "Founders" podcast, where he delves into biographies of history's greatest entrepreneurs, extracting lessons and insights for his audience. In the conversation, he emphasizes the critical role of storytelling in entrepreneurship, highlighting that the most effective storytellers are often founders themselves, as they possess an intrinsic understanding and passion for their company's mission. He underscores the importance of founders being deeply involved in communicating their vision, as this authenticity and dedication are challenging to replicate through external hires.
TBPN.com is made possible by:
Ramp - https://ramp.com
Figma - https://figma.com
Vanta - https://vanta.com
Linear - https://linear.app
Eight Sleep - https://eightsleep.com/tbpn
Wander - https://wander.com/tbpn
Public - https://public.com
AdQuick - https://adquick.com
Bezel - https://getbezel.com
Numeral - https://www.numeralhq.com
Attio - https://attio.com/tbpn
Fin - https://fin.ai/tbpn
Graphite - https://graphite.dev
Restream - https://restream.io
Profound - https://tryprofound.com
Julius AI - https://julius.ai
turbopuffer - https://turbopuffer.com
Polymarket - https://polymarket.com/
fal - https://fal.ai
Privy - https://www.privy.io
Cognition - https://cognition.ai
Gemini - https://gemini.google.com
Follow TBPN:
https://TBPN.com
https://x.com/tbpn
https://open.spotify.com/show/2L6WMqY3GUPCGBD0dX6p00?si=674252d53acf4231
https://podcasts.apple.com/us/podcast/technology-brothers/id1772360235
https://www.youtube.com/@TBPNLive
The AI-powered Podcast Player
