What do a comic genius and an internationally renowned psychiatrist have in common? Quite a bit, it turns out. So much, in fact, that Harper’s Magazine and Book Culture on Columbus brought John Cleese and Iain McGilchrist together for two nights of conversation. On the first night, McGilchrist interviewed Cleese; on the second, Cleese interviewed McGilchrist. With wit and intelligence, the two men delved into the philosophical and biological underpinnings of how we each understand the world.

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