The Joy of Why cover image

Why Do We Die Without Sleep?

The Joy of Why

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Hypocreten Directon

There's a protein called hypocreten directon that is released from nerons and binds to receptor. It caused the dogs, when they would get excited, to essentially fall asleep with cataplexy. And then later found that humans with narcylepsy often had a loss of hypo retan neurons in their hypothalymus. We just found in cave fish that variable levels of this gen track with how much the fish sleeps. And so it's possible that this translates to humans as well. Really good sleepers might have lower levels of hypocretan. And poor sleepers or insomniacs might have higher levels of thisgen.

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