PTSD is the syndrome where it's most demonstrated. You see expansion of the amygdala and you see atrophy of the hippocampus, glucocorticoids probably play the driving role in both. The problem with chronic stress in the amygdala is it works better than it's supposed to. Stress makes people crappier to each other and less empathic and more parochial when they're in pain.
View the Show Notes Page for This Episode
Become a Member to Receive Exclusive Content
Sign Up to Receive Peter’s Weekly Newsletter
In this episode, Robert Sapolsky, Ph.D., discusses the widespread impact of stress on our physical and emotional health as well as the mechanisms by which it can precipitate chronic illness, dementia, depression, and more. He also provides insight into the factors that contribute to the stress response (and our ability to handle it) such as social rank, personality, environment, and genetics. Lastly, we discuss how our behavior is altered in the face of stress and how that not only has a pervasive effect on a personal level, but also on society as a whole in how we interact with each other.
We discuss:
- Background, interest in stress, and Robert’s time in Kenya studying baboons [2:45];
- Physiology of a stress response, and why it’s ingrained in our DNA [9:45];
- Individual variation in the response to stress, and how everyone has a different optimal level [19:45];
- How social rank and personality differences affect our stress response [26:30];
- What’s happening in the brain when faced with stressful situations? [35:00];
- What makes the human brain different than all other species? [44:15];
- Imprinting stress to your kids epigenetically [48:00];
- The role of stress on memory and the consequences of hypercortisolemia [53:00];
- The impact of subjective socioeconomic status and social media on stress levels and health [57:45];
- Tips for managing stress in the modern world [1:13:15];
- What Robert learned about himself studying the social behavior of baboons [1:25:30];
- The multilayered factors behind every human behavior, the context of “good and bad”, and exploring the human capacity of the wild extremes of violence and altruism from moment to moment [1:30:15];
- PMS: How two women with identical hormone levels can have completely different emotional experiences [1:34:45];
- How much of a role do genes play in depression and other emotional states? [1:38:00];
- Why is cortisol elevated under sleep deprivation? [1:46:00];
- The impact of stress on cancer [1:50:30];
- The impact of stress on atherosclerosis, dementia, addiction, and depression [1:57:00];
- Impulsiveness, impaired judgment, and lack of empathy in times of stress [2:01:45];
- What advice would Robert give his 25-year-old self? [2:08:45]; and
- More.
Connect With Peter on Twitter, Instagram, Facebook and YouTube
