Central Sleep Apnea - What Is It?

There are multiple pathways for central apnea but the one that's most relevant to us is the dependence on CO2 levels. So as during wakefulness if we hyperventilate and lower our CO2 we will not stop breathing because of a cortical drive. But during non-rem sleep, if we decrease the CO2 by a certain amount we will go apnea. And I always tell when I talk about central apnea I can induce central apnea in every human.