The Role of Arachidonic Acid in Immunity

Question: If I don’t want to hurt my omega 6 status through my omega 3 intake, how do I do that? Is it simply a question of taking them at separate times? Or is it a question of dose? And if it is a question of dose, how do I know when to start eating fish and taking my omega 3 supplement again?

Short Answer: How they are combined in meals is not important, but it is important not to have too much EPA in cell membranes relative to arachidonic acid, and this is driven by cumulative intake over years. For someone who has consumed too much EPA for many years, the best approach is to eat liver and egg yolks for arachidonic acid while getting omega-3s from a DHA supplement and not from fish, fish oil, or fish liver oil.

This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

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In that batch of free episodes you will also find the answers to these questions:

• Can plant foods and their phytochemicals be used to reduce arterial plaque?

• If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?

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This snippet is from the January 21, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what’s included:

• Can plant foods and their phytochemicals be used to reduce arterial plaque?

• If I have a hereditary weakness in breaking down branched-chain amino acids, what cofactors do I need to consider, and do I need to restrict my protein when losing weight?

• Could carnitine help a fatty acid oxidation disorder?

• Should anti-inflammatories be taken away from workouts?

• How does vitamin C affect autoimmune disease?

• Folate form and purines

• Can methylene blue help the respiratory chain?

• Best references for omega-3 and inflammation resolution?

• Smoothies and blood sugar

• Is transdermal magnesium oil effective for osteoarthritis?

• Why do K2 and Mg help my nerve pain?

• Should I separate my potassium benzoate and vitamin C supplements?

• The best and most simple comprehensive micronutrient panel.

• How much K2 is needed in pregnancy?

• How do I accentuate the fasting-feeding cycle?

• Could K2 help with environmental pollution?

• Why do shoulders crack when we get older?

• Why do I react poorly to anti-inflammatory foods?

Here’s a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-january  Access the show notes, transcript, and comments here.