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22min chapter
Intellia and Ultragenyx’s Clinical Updates, Novo Holdings’ Catalent Acquisition, and NanoString Bankruptcy; Simon Barnett
Touching Base
Intersection of Machine Learning and Biophysics in Structural Biology
This chapter discusses the intersection of machine learning and biophysics in the field of structural biology. It highlights the importance of combining classical methods with machine learning methods in order to achieve meaningful results in drug design tasks. Topics include cryo EM and molecular dynamics for protein modeling, ML-based methods for molecule screening and scoring, and the concept of a learned force field.
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