TWiV 1115: Calling the CoPs on flu
This Week in Virology
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Immune Responses and Correlates of Protection Against Influenza Infection
This chapter explores a study that analyzes immune responses in vaccinated and unvaccinated individuals to identify correlates of protection against influenza virus infection separate from serology. Researchers focus on the importance of T-cell populations, especially in vaccinated individuals, and delve into specific cell populations like T follicular helper cells and CD4 cells producing cytokines. The study aims to provide insights for vaccine developers by determining threshold levels for specific parameters and by analyzing clusters of cells crucial for protection in different groups.
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