Juicebox Podcast: Type 1 Diabetes cover image

#934 iLet Bionic Pancreas with Ed Damiano

Juicebox Podcast: Type 1 Diabetes

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The Effects of Glucagon on the Bio-Monautal System

You're not going to get to a point with a bio-monautal system where you'd get depleted unless you were very sick, right? So suppose you've been, you had a vomiting illness and you haven't been getting, keeping anything down for a few days. You could get into a situation where you're depleted of glycogen stores. And then there's no substrate upon which glucagon can act if there's no glycogen stored. But that's hard to get to; we never saw any depletion of glycogen storage in our trials.

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