The Evolution of the TDT Enzyme

The core engine that really drives our enzymatic synthesis process is a proprietary TDT enzyme. It was such an evolved project that we end up going through 40 rounds of evolution and over what 1.3 million variants ended up in an amino acid sequence change of over 25%. So you're talking about over a quarter of the profile of this TDT enzyme that's been changed. And where did this enzyme come from, Mike? Maybe you want to answer that one.

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