TDXD - A New Antibody Drug Conjugate Compared to TDM1

TDXD is a new antibody drug conjugate compared to TDM1. It's the same Trastuzumab backbone, but it has a different warhead. The linker linking the warhead to the missile is also a slightly different linker in terms of engineering. Even with some tumor heterogeneity, it can still go around and kill neighboring cancer cells. And we have seen activity in the TDM1 resistant breast cancers initially.