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Psychedelics
Fivemath oxy parolitin trip tomean was a known compound, but it was not known that it exerted a very different type of activity from d m t. Some of the most selective known five h t one a agnes are five m o prolityn triptian derivatives. And i think those ar were all synthesized in the nichols lab after you left. I don't think anyone would have been aware of that unless some one like you had tried it.