Phenobarbital vs. Benzodiazepines in Alcohol Withdrawal Treatment

Exploring the shift in alcohol withdrawal treatment from phenobarbital to benzodiazepines, this chapter details the efficacy of phenobarbital, emphasizing its unique pharmacological properties and safe dosage ranges. It discusses a study showing promising results of phenobarbital in the emergency department and underlines its effectiveness in sedating patients refractory to benzodiazepines. The chapter highlights the advantages of phenobarbital in addressing GABA deficiency and excessive glutamate activity in alcohol withdrawal.