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John Ioannidis on Statistical Significance, Economics, and Replication

EconTalk

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I'm Not Going to Do a Round Trial, but I Don't Think That Would Be a Good Investment

There's a continuum, and each field is operating in a different point within that continuum. I don't think that someone would do a round trial. They're going to share something, trust me. So these needles are few, and most of what we're going to be detected is likely to be false positive unless we find ways to further document that what we have found is really true.

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