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Ep. 54: “Innate and Mucosal Immunity” Featuring Dr. Bana Jabri

The Immunology Podcast

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The Role of TCRs in the Regeneration of Viral Mice

The mice are transducing hematopoeidic stem cells from rag one negative one rag one knockout mice and then they regenerate uh with the jamaic bone marcomeras. They use this in order to understand like well we have this this all these tetramar positive cells that we identified from the naive repertoire what happens if we we barcode them? It's also I think very very interesting but it must have been a very time consuming very laborious system to take to work with. The results showed actually many of these TCRs that they picked up with barcode are not actually specific they're actually not responding to antigen.

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